LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD44
Background: Radiotherapy is the primary treatment for patients with nasopharyngeal carcinoma (NPC); however, almost 20% of patients experience treatment failure due to radioresistance.Therefore, understanding the mechanisms of radioresistance is imperative.HOTAIRM1 is deregulated in various human cancers, yet its role in NPC radioresistance are lar